Treatment of nausea and emesis during cancer chemotherapy

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5 In preventing an early onset of PONV (nausea and vomiting occurring 0–6 hours after surgery is considered an early onset of PONV; nausea and vomiting occurring after 6–24 hours is considered to be a late onset of PONV), dexamethasone In two previous consecutive studies on antiemetic combination of metoclopramide and dexamethasone was found to be very active against nausea and vomiting induced by cisplatin (DDP; 50 mg/m2) alone or in combination with other cytotoxic emetogenic drugs. 2000-04-01 · Dexamethasone was first reported as an effective antiemetic in patients receiving cancer chemotherapy in 1981.16 Since then, several studies have shown that dexamethasone is equal to or better than other antiemetic agents in preventing the nausea and vomiting associated with chemotherapy.1719 Recently, dexamethasone has also been reported to be effective in preventing PONV in patients receiving tonsillectomy, thyroidectomy and abdominal hysterectomy.913 Therefore, we Abstract We conducted a randomized, double-blind, crossover study comparing the antiemetic efficacy of dexamethasone and prochlorperazine in 42 patients with cancer who were receiving outpatient ch Furthermore, 8 mg and 16 mg dexamethasone have equivalent antiemetic efficacy. The results suggest that granisetron and dexamethasone combination therapy is useful in controlling acute and delayed nausea and vomiting induced by CDDP-containing chemotherapy for head and neck cancer. Postoperatively for 24 hours observation and assessment of nausea, vomiting, rescue anti-emetics, and side effects of the study drugs such as headache and drowsiness were carried out.

and cancer ( Phys-Can) the impact of exercise intensity on cancer related fatigue, Discrepancies between antiemetic effect and well-being2002Ingår i: Journal of Aspects of delayed chemotherapy-induced nausea: Dexamethasone and av M Sharifi-Jahanfard · 2011 · Citerat av 1 — Treatment of nausea and emesis during cancer chemotherapy: Discrepancies between antiemetic effect and well-being. Journal of pain and symptom metoclopramide plus dexamethasone in prevention of nausea and vomiting induced by Discrepancies between antiemetic effect and well-being. J Pain Hesketh PJ et al. Evaluation of new antiemetic agents and granisetron plus dexamethasone for prevention of nausea and vomiting during side effects. av M Wattwil — lactic effect of dexamethasone on postoperative nausea and vomiting in women undergoing effectiveness, and cost-benefit as a prophylactic antiemetic in the. with Rimcure because of the neurotoxic effects of isoniazid.

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Prophylactic antiemetic effect of dexamethasone in women undergoing ambulatory laparoscopic surgery. @article{Wang2000ProphylacticAE, title={Prophylactic antiemetic effect of dexamethasone in women undergoing ambulatory laparoscopic surgery.}, author={J. J. Wang and S. Ho and H. Liu and C. M. Ho}, … 2020-06-17 CiteSeerX - Document Details (Isaac Councill, Lee Giles, Pradeep Teregowda): Objectives: To evaluate the antiemetic effect of a single dose of ondansetron and dexamethasone as a prophy-laxis for chemotherapy induced acute nausea and emesis and factors associated with the control of acute nausea and emesis.

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The etiology of PONV in patients undergoing abdominal total hysterectomy is not fully understood. BACKGROUND Nausea and vomiting are frequently seen in patients undergoing cesarean section (CS) under regional anesthesia. We aimed to compare the antiemetic efficacy of ondansetron and dexamethasone combination with that of the use of each agent alone to decrease the incidence of post-delivery intraoperative nausea and vomiting (IONV) during CS under spinal anesthesia.
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Lancet 1991 Aug 24 Both dexamethasone and ondansetron, a serotonin antagonist recently approved by the FDA, have been successfully used to prevent the nausea and vomiting induced by chemotherapy. . . .

CC: A risk score-dependent antiemetic approach effectively reduces The Effect of Intravenous Midazolam on Postoperative Nausea and ”Reconsidering the effects of monosodium glutamate: a literature review”. ”Ibuprofen with or without an antiemetic for acute migraine headaches in adults”.
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General anesthesia with inhalation agents was used for all the patients. The incidence and severity of PONV, administration of rescue antiemetic, and the side effects of the antiemetic were documented during the first 48 h after surgery. Results: The incidence of Their effect as an antiemetic is more likely related to anxiolysis and mitigation of anticipatory emesis rather than a direct effect on the area postrema (13). Glucocorticoids, particularly dexamethasone, has well-established antiemetic properties and is used to treat chemotherapy-induced vomiting (14). Nausea and vomiting are common symptoms with many possible causes, including the adverse effects of drugs.

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Glucocorticoids, particularly dexamethasone, has well-established antiemetic properties and is used to treat chemotherapy-induced vomiting (14). Nausea and vomiting are common symptoms with many possible causes, including the adverse effects of drugs.

Dexa- methasone has been used as an antiemetic for more than 10 yr in patients receiving chemotherapy, with limited side effects [7–11]. The mechanism of Jan 25, 2016 Corticosteroids as antiemetic drugs · unknown mechanism of action (with respect to antiemetic effects) · commonly used in in combination with a The glucocorticoids had a direct inhibitory effect on 5-HT3 receptors. such as dexamethasone and methylprednisolone have antiemetic effects on patients Jul 15, 2004 Do 5-hydroxytryptamine3 receptor antagonists (5-HT3) improve the antiemetic effect of dexamethasone for preventing delayed release from the gut and increasing the response to other antiemetics at a Research on clinically significant antiinflammatory effects of dexamethasone in Jan 5, 2014 Dexamethasone, one of the glucocorticoids, has been suggested as a first-line drug for preventing low-level emetogenic chemotherapy- and Sep 4, 2013 Antiemetic effects of dexamethasone and ondansetron combination during cesarean sections under spinal anaesthesia. A Demirhan; YU Nov 9, 2020 Dexamethasone is a potent and highly selective long acting glucocorticoid. The precise mechanism of its antiemetic action is not known but may Apr 1, 2020 Corticosteroids such as dexamethasone (4–8 mg daily) are effective at managing chemotherapy-induced nausea and vomiting, bowel obstruction PONV without producing additional side effects [17]. Dexamethasone has been used as an antiemetic for more than 20 years in patients receiving chemotherapy. Aug 10, 2020 The corticosteroid dexamethasone is used in multiple antiemetic in the data that dexamethasone somehow negated the effects of checkpoint Oct 4, 2004 Chronic nausea occurs in most patients with advanced cancer.